Project reports

• Lead Bioinformatician@Applied Spatial Omics Centre
  Jan 2024 - present

[Biomarker discovery]
1. [Spatial Tx] Spatial Transcriptomics Revealed Alzheimer's Disease Associated Parvalbumin Interneurons Molecular Markers.



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• Lead Bioinformatician@Morrissy Lab
  Nov 2020 - Dec 2023

[Biomarker discovery]
1. [RNA] Spatial gene expression profiling in GBM
2. [Methylation] Establishing epigenetic signatures using PCDHs

[Notes/scratch]
1. [Protein] Identification of target proteins for the spike-in library



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• PostDoc@BHK Lab
  Jan 2018 - Oct 2020

[Biomarker discovery]
1. [WGS] Cancer recurrence biomarkers in early-stage PDAC with gemcitabine adjuvant chemotherapy
2. [WGS] Gemcitabine response prediction and assessment in PDAC PDOs
3. [Cell line] Gemcitabine resistance biomarkers of ITCH and CD73
4. [Cell line] Associations between NEK10 expression and drug/radio responses
5. [Cell line] NT5E (CD73) expression and survival analysis in PDAC
6. [RNA] Hypoxia signature genes in PDAC
7. [RNA] Systematic evaluation of CDADC1 expression in vitro
8. [Organoids] Pharmacological profiles of advanced PDAC PDOs in COMPASS
9. [Organoids] Pancreatic derived organoid platform for BET inhibitor testing

[Database/Tool]

1. [Web-app] SYNERGxDB
2. [Prototype] cdCocktails
• [Preprocessing] Synergy score calculation

[Notes/scratch]
1. [GDSC1000] Gemcitabine biomarkers in pancreatic cancer
2. Jupyter notebook for biomarker discovery on Azure Databricks



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• Master/PhD student@SNUBI
  Sep 2010 - Dec 2017

[Biomarker discovery]
1. [MICROARRAY] AgiMicroRNA R Package Analysis
2. [ArrayCGH] Copy number of Squamous cell carcinoma in non-smokers
3. [RNA] Nephrotic syndrome
4. [RNA] Chmp5 Knock-out mice
5. [WXS] Eosinophilia
6. / [WXS] Ritodrine induced side-effects
7. [PANEL] Mercaptopurine neutropenia in ALL
8. [PANEL] Busulfan hepatotoxicity in AML
9. [PANEL] Ritodrine induced side-effects

[Genetic predisposition]
1. [Analysis] Assessment of rare germline mutations for cancer susceptibility with synthetic association study
2. [Analysis] Variant, Gene, and Drug scores in Pharmacogenomics

[Knowledge Base/Tools]
1. [KB] Korean Rare disease Knowledge Base
2. [TOOL] CaReAl: Capturing Read Alignments
3. [TOOL] VVA: Variant Visualization and Annotation

[Note/scratch]
1. [1000 Genomes] Data statisitcs and description
2. [TCGA] Germline data statistics
3. [RNA] Illumina Human Bodymap
4. [SERVICE] Available services
5. Package source code
• KSBMB Wep-app source code
• PHP ping source code, Server stats
• Web excel in javascript, TCGA-BRCA



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